- 询价
- BIO-RAD
- MCA686S
- 2025年10月17日
- C, P
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Human myelin basic protein.
- 亚型：
IgG2b
- 形态：
Tissue Culture Supernatant - liquid
- 克隆性：
Monoclonal Antibody
- 标记物：
S/N
- 适应物种：
Human
- 保质期：
自发货之日起 12 个月
- 目录编号：
22
- 供应商：
伯乐生命医学产品（上海）有限公司
- 应用范围：
C, P
- 抗体名：
MBP antibody | 22
- 规格：
2 ml
Mouse anti MBP antibody, clone 22 recognizes an epitope between amino acids 84 and 89 of human myelin basic protein, also known as MBP, Myelin A1 protein or Myelin membrane encephalitogenic protein. MBP is a 304 amino acid ~33 kDa abundant component of the myelin membrane. There are 6 potential isoforms of MBP generated by alternative splicing, 4 of which lack the N-terminal region containing the immunogen sequence. Mouse anti MBP antibody, clone 22 is expected to recognize isoforms 1 and 2 (UniProt: P02686). The N-terminal region of MBP is highly conserved and Mouse anti MBP antibody, clone 22 is expected to be broadly species cross reactive for isoforms maintaining the N-terminal region. Mouse anti MBP antibody, clone 22 has been reported as suitable for use in western blotting (Chignola et al. 2000).
储存信息
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunohistology - Frozen | ✓ | ||
| Immunohistology - Paraffin | ✓ |
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- Histology Positive Control Tissue
- Brain
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文献和实验该产品被引用文献
References for MBP antibody
- Martenson, R. E. (1984) Experimental allergic encephalomyelitis. A useful model of multiple sclerosis.
Eds Alvord, Kies and Suckling pp 511-521. Alan Liss N.Y. - Groome, N. et al. (1988) New monoclonal antibodies reactive with defined sequential epitopes in human myelin basic protein.
J Neuroimmunol. 19 (4): 305-15. - Diemel, L.T. et al. (2003) Role for TGF-beta1, FGF-2 and PDGF-AA in a myelination of CNS aggregate cultures enriched with macrophages.
J Neurosci Res. 74 (6): 858-67. - Harrower, T.P. et al. (2006) Long-term survival and integration of porcine expanded neural precursor cell grafts in a rat model of Parkinson's disease.
Exp Neurol. 197 (1): 56-69. - Liao, M.C. et al. (2009) Degradation of amyloid beta protein by purified myelin basic protein.
J Biol Chem. 284: 28917-25.
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文献支持
Mouse anti Human MBP (aa84-89)，clone 22
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