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- 详细信息
- 技术资料
- 免疫原:
Full length recombinant human CD171 (NP_000416) produced in HEK293T cells
- 亚型:
IgG1
- 形态:
Purified IgG - liquid
- 克隆性:
PrecisionAb Monoclonal
- 标记物:
Purified
- 适应物种:
Human
- 保质期:
自发货之日起 12 个月
- 目录编号:
OTI2G9
- 供应商:
伯乐生命医学产品(上海)有限公司
- 应用范围:
IP, WB
- 浓度:
IgG concentration 0.5 mg/ml.
- 抗体名:
CD171 antibody | OTI2G9
- 规格:
100 µl
Mouse anti Human CD171 antibody, clone OTI2G9 recognizes the CD171 antigen, also known as neural cell adhesion molecule L1, antigen identified by monoclonal antibody R1 and neural cell adhesion molecule L1.
Encoded by L1CAM gene, CD171 is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of L1CAM results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons (provided by RefSeq, May 2013).
Mouse anti Human CD171 antibody, clone OTI2G9 detects a band of 220-240 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Encoded by L1CAM gene, CD171 is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of L1CAM results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons (provided by RefSeq, May 2013).
Mouse anti Human CD171 antibody, clone OTI2G9 detects a band of 220-240 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
储存信息
This product is shipped at ambient temperature.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunoprecipitation | ✓ | ||
| Western Blotting | ✓ | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Learn about how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Mouse anti CD171,clone OTI2G9
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