- 询价
- BIO-RAD
- MCA2125
- 2025年10月17日
- F
- Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
RIL-2 propagated NK1.1+ cells from C57BL/6 mice.
- 亚型：
IgM
- 形态：
Purified IgM - liquid
- 克隆性：
Monoclonal Antibody
- 标记物：
Purified
- 适应物种：
Mouse
- 保质期：
自发货之日起 12 个月
- 目录编号：
DX5
- 供应商：
伯乐生命医学产品（上海）有限公司
- 应用范围：
F
- 浓度：
IgM concentration 0.5 mg/ml
- 抗体名：
CD49b antibody | DX5
- 规格：
0.25 mg
Rat anti Mouse CD49b monoclonal antibody, clone DX5 recognizes mouse CD49b, also known as Very Late Antigen-2 (VLA-2) or alpha-2 integrin. CD49b is a ~160kDa single pass type I membrane protein expressed by NK cells and a small subset of T-cells (Pellicci et al. 2005).
Rat anti mouse CD49b, clone DX5 stains NK cells from all mouse strains tested including Balb/c mice (Arese et al. 2001). CD49b acts as a receptor for collagen, laminin, fibronectin and E-cadherin (Carafoli et al. 2013).
Rat anti mouse CD49b, clone DX5 stains NK cells from all mouse strains tested including Balb/c mice (Arese et al. 2001). CD49b acts as a receptor for collagen, laminin, fibronectin and E-cadherin (Carafoli et al. 2013).
储存信息
This product is shipped at ambient temperature.
Store at +4°C.
DO NOT FREEZE
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
Store at +4°C.
DO NOT FREEZE
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry | ✓ | ||
| Immunohistology - Frozen | × | ||
| Immunohistology - Paraffin | × |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10μl of the suggested working dilution to label 106 cells in 100μl
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文献和实验该产品被引用文献
References for CD49b antibody
- Arase, H. et al. (2001) Cutting edge: the mouse NK cell-associated antigen recognized by DX5 monoclonal antibody is CD49b (alpha 2 integrin, very late antigen-2).
J Immunol. 167 (3): 1141-4. - Jacobs, N. et al. (2006) Intradermal immune response after infection with Vaccinia virus.
J Gen Virol. 87: 1157-61. - Yin, Y. et al. (2013) Phosphatidylserine-targeting antibody induces M1 macrophage polarization and promotes myeloid-derived suppressor cell differentiation.
Cancer Immunol Res. 1 (4): 256-68. - Lin, C.Y. et al. (2008) Combined immunogene therapy of IL-6 and IL-15 enhances anti-tumor activity through augmented NK cytotoxicity.
Cancer Lett. 272: 285-95. - Thomson, R.C. et al. (2008) Expansion and activation of NK cell populations in a gammaherpesvirus infection.
Scand J Immunol. 67: 489-95. - Pais, R. et al. (2012) An intracameral injection of antigen induces in situ chemokines and cytokines required for the generation of circulating immunoregulatory monocytes.
PLoS One. 7: e43182.
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文献支持
Rat anti Mouse CD49b，clone DX5
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