- 询价
- BIO-RAD
- MCA2256
- 2025年10月17日
- WB
- Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Purified recombinant extracellular region of mouse CDw210a.
- 亚型：
IgG1
- 形态：
Purified IgG - liquid
- 克隆性：
Monoclonal Antibody
- 标记物：
Purified
- 适应物种：
Mouse
- 保质期：
自发货之日起 12 个月
- 目录编号：
1B1.3a
- 供应商：
伯乐生命医学产品（上海）有限公司
- 应用范围：
WB
- 浓度：
IgG concentration 1.0 mg/ml
- 抗体名：
CDw210a antibody | 1B1.3a
- 规格：
0.25 mg
Rat anti Mouse CDw210a antibody, clone 1B1.3a recognizes mouse CDw210a, a cell surface glycoprotein of approximately 110 kDa, also known as Interleukin-10 receptor 1 (IL-10R1). The epitope recognized by this antibody has been localised to the ligand binding domain within the extracellular region of mouse CDw210a. Mouse CDw210a is expressed by a range of cells including thymocytes, T cells, B cells and monocytes. Rat anti Mouse CDw210a antibody, clone 1B1.3a is reported to neutralize the effects of IL-10 (Asseman et al. 1997).
储存信息
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | ✓ | 1/200 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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文献和实验该产品被引用文献
References for CDw210a antibody
- Asseman, C. et al. (1999) An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation.
J Exp Med. 190 (7): 995-1004. - Phillips, J.M. et al. (2001) Cutting edge: interactions through the IL-10 receptor regulate autoimmune diabetes.
J Immunol. 167 (11): 6087-91. - Iwashiro, M. et al. (2001) Immunosuppression by CD4+ regulatory T cells induced by chronic retroviral infection.
Proc Natl Acad Sci U S A. 98: 9226-30. - Montagnoli, C. et al. (2002) B7/CD28-dependent CD4+CD25+ regulatory T cells are essential components of the memory-protective immunity to Candida albicans.
J Immunol. 169: 6298-308. - Vicari, A.P. et al. (2002) Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody.
J Exp Med. 196: 541-9. - Sundstedt, A. et al. (2003) Role for IL-10 in suppression mediated by peptide-induced regulatory T cells in vivo.
J Immunol. 170 (3): 1240-8. - Asseman, C. et al. (2003) Colitogenic Th1 cells are present in the antigen-experienced T cell pool in normal mice: control by CD4+ regulatory T cells and IL-10.
J Immunol. 171: 971-8.
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文献支持
Rat anti Mouse CDw210a，clone 1B1.3a
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