- 询价
- BIO-RAD
- MCA2408GA
- 2025年10月17日
- E, F, IP
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG1
- 形态：
Purified IgG - liquid
- 克隆性：
Monoclonal Antibody
- 标记物：
Purified
- 适应物种：
Human
- 保质期：
自发货之日起 12 个月
- 目录编号：
10F2
- 供应商：
伯乐生命医学产品（上海）有限公司
- 应用范围：
E, F, IP
- 浓度：
IgG concentration 1.0 mg/ml
- 抗体名：
CD178 antibody | 10F2
- 规格：
0.1 mg
CD178 is a member of the TNF family, which is expressed by activated T lymphocytes and NK cells. The protein may exist as either a membrane bound or a cleaved soluble form.
CD178 plays an important role in T cell development and cytotoxicity. Binding of CD178 to Fas (CD95) results in the induction of apoptosis.
Mouse anti Human CD178 antibody, clone 10F2 is reported to block the activity of Fas ligand (Legembre et al. 2002).
储存信息
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA | ✓ | ||
| Flow Cytometry | ✓ | 1/25 | 1/50 |
| Immunoprecipitation | ✓ | ||
| Western Blotting | × |
- Flow Cytometry
- Use 10μl of the suggested working dilution to label 1x106 cells in 100μl
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文献和实验References for CD178 antibody
- Legembre, P. et al. (2002) Potentiation of Fas-mediated apoptosis by an engineered glycosylphosphatidylinositol-linked Fas.
Cell Death Differ. 9 (3): 329-39. - Ferry-Dumazet, H. et al. (2002) Resveratrol inhibits the growth and induces the apoptosis of both normal and leukemic hematopoietic cells.
Carcinogenesis. 23 (8): 1327-33. - Thorén, F.B. et al. (2012) Human NK Cells induce neutrophil apoptosis via an NKp46- and Fas-dependent mechanism.
J Immunol. 188 (4): 1668-74. - Pellegrin, S. et al. (2012) Differential proteomic analysis of human erythroblasts undergoing apoptosis induced by epo-withdrawal.
PLoS One. 7 (6): e38356. - Morello, A. et al. (2013) Enhancing production and cytotoxic activity of polymeric soluble FasL-based chimeric proteins by concomitant expression of soluble FasL.
PLoS One. 8 (8): e73375. - Robinet, P. et al. (2014) A polysaccharide virulence factor of a human fungal pathogen induces neutrophil apoptosis via NK cells.
J Immunol. 192 (11): 5332-42. - Pugholm, L.H. et al. (2016) Phenotyping of Leukocytes and Leukocyte-Derived Extracellular Vesicles.
J Immunol Res. 2016: 6391264.
Immunohistochemistry: Mouse Anti-Human MCP-1
. 4. Incubate the tissue section overnight at 4?C with Mouse Anti-Human MCP-1 at 10.0 μg/mL. Wash the slide twice for three minutes each. 5. Incubate the tissue section with the Envision HRP polymer kit (Dako) according to the manufacturer’s
Aspects of CNS Lupus: Mouse Models of Anti-NMDA Receptor Antibody Mediated Reactivity
transfer of pathology by injecting human and mouse brain-reactive antibodies into adult mouse as well as injecting the antibody into gestating mice and transfer of antibody from dam to fetus, (5) blocking NMDAR-mediated pathogenicity in vivo, (6) evacuation
Th17 Polarization of Mouse CD4 Cells
实验试剂 Sterile PBS Cell culture medium Sterile plastic petridishes RBC Lysis Buffer [Details: Biolengend, cat.#420301] Anti-mouse CD3ε, clone145-2C11[Details: LEAF™format, cat.#100314]
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