- 询价
- BIO-RAD
- AHP2697
- 2025年10月17日
- P, WB
- Human
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- 详细信息
- 技术资料
- 免疫原：
Phospho specific-peptide corresponding to residues surrounding serine 276 of human NFkB p65
- 亚型：
NFkB p65 (pSer276)
- 形态：
Purified IgG - liquid
- 克隆性：
Polyclonal Antibody
- 标记物：
Purified
- 适应物种：
Human
- 保质期：
自发货之日起 12 个月
- 目录编号：
Polyclonal IgG
- 供应商：
伯乐生命医学产品（上海）有限公司
- 应用范围：
P, WB
- 抗体名：
NFkB p65 (pSer276) antibody
- 规格：
50 µl
Rabbit anti NFkB p65 (pSer276) antibody recognizes nuclear factor NF-kappa-B p65 subunit (NFkB3 p65) also known as transcription factor p65 or RELA, when phosphorylated at serine 276. NFkB p65 is part of the NFkB transcription factor complex that also includes RELB, NFkB1 p105, NFkB1 p50, REL and NFkB2 p52. NFkB p65 regulates expression of a wide variety of genes involved in immune and inflammatory responses (May, M.J. & Ghosh, S. 1997). Protein kinase A (PKA) phosphorylates NFkB p65 on serine 276 and modulates transcriptional activity of NFkB by mediating its interaction with CBP/p300 (Zhong, H. et al. 1998). Serine 276 has also been demonstrated to be phosphorylated by mitogen- and stress- activated protein kinase-1 (MSK1) (Vermeulen, L. et al. 2003). The NFkB pathway plays a critical role in orchestrating immune responses after infection and has been implicated in a variety of diseases ranging from autoimmune disorders to cancer.
储存信息
This product is shipped at ambient temperature.
Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunohistology - Paraffin | ✓ | 1/50 | 1/100 |
| Western Blotting | ✓ | 1/500 | 1/2000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Rabbit anti NFkB p65 (pSer276)
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