- 询价
- BIO-RAD
- MCA453GA
- 2025年10月17日
- C, F, IP
- Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Rat T blasts and erythrocytes.
- 亚型：
IgG1
- 形态：
Purified IgG - liquid
- 克隆性：
Monoclonal Antibody
- 标记物：
Purified
- 适应物种：
Rat
- 保质期：
自发货之日起 12 个月
- 目录编号：
R73
- 供应商：
伯乐生命医学产品（上海）有限公司
- 应用范围：
C, F, IP
- 浓度：
IgG concentration 1.0 mg/ml
- 抗体名：
TCR Alpha/Beta antibody | R73
- 规格：
0.1 mg/0.25 mg
| 规格： | 0.1 mg | 产品价格： | 询价 |
|---|---|---|---|
| 规格： | 0.25 mg | 产品价格： | 询价 |
Mouse anti Rat TCR alpha/beta antibody, clone R73 recognizes a constant determinant on the beta chain of the rat alpha/beta T cell receptor, expressed by 97% of peripheral rat T cells as defined by the OX-52 marker. R73 is mitogenic for unseparated spleen cells and for purified T cells. In the rat thymus, mature medullary cells express the R73 determinant at the same levels as peripheral T cells, whereas 94% of CD4 - CD8 - thymocytes are R73 negative.
Mouse anti Rat TCR alpha/beta antibody, clone R73 is reported to stimulate adhesion between Thymic Dendritic Cells and Thymocytes (Colic et al. 2010).
Mouse anti Rat TCR alpha/beta antibody, clone R73 is reported to stimulate adhesion between Thymic Dendritic Cells and Thymocytes (Colic et al. 2010).
储存信息
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry | ✓ | 1/50 | 1/100 |
| Immunohistology - Frozen | ✓ | 1/10 | 1/100 |
| Immunoprecipitation | ✓ |
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 100ul of whole blood or 106 cells in 100ul.
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文献和实验该产品被引用文献
Source Reference
- Hünig, T. et al. (1989) A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. Differential reactivity with subsets of immature and mature T lymphocytes.
J Exp Med. 169 (1): 73-86.
References for TCR Alpha/Beta antibody
- Tomida, S. et al. (1994) Intercellular adhesion molecule-1 and leukocyte function-associated antigen-1 are involved in protection mediated by CD3+TCR alpha beta- T cells at the early stage after infection with Listeria monocytogenes in rats.
Int Immunol. 6 (7): 955-61. - Colić, M. et al. (1996) Mechanisms involved in the binding of thymocytes to rat thymic dendritic cells.
Dev Immunol. 5 (1): 37-51. - Kanellis, J. et al. (2010) JNK signalling in human and experimental renal ischaemia/reperfusion injury.
Nephrol Dial Transplant. 25: 2898-908. - Nave, H. et al. (2008) Resistance of Janus kinase-2 dependent leptin signaling in natural killer (NK) cells: a novel mechanism of NK cell dysfunction in diet-induced obesity.
Endocrinology. 149: 3370-8. - Tsuchida, M. et al. (1994) Identification of CD4- CD8- alpha beta T cells in the subarachnoid space of rats with experimental autoimmune encephalomyelitis. A possible route by which effector cells invade the lesions.
Immunology. 81 (3): 420-7. - Matsumoto, Y. et al. (1994) Successful prevention and treatment of autoimmune encephalomyelitis by short-term administration of anti-T-cell receptor alpha beta antibody.
Immunology. 81 (1): 1-7. - Pilipović, I. et al. (2010) Glucocorticoids, master modulators of the thymic catecholaminergic system?
Braz J Med Biol Res. 43 (3): 279-84. - Milicevic, N.M. et al. (2005) T cells are required for the peripheral phase of B-cell maturation.
Immunology. 116: 308-17.
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Mouse anti Rat TCR Alpha/Beta，clone R73
询价
