- 询价
- BIO-RAD
- MCA4661F
- 2026年01月25日
- F
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
NIH3T3 cells expressing full length Beta-glucan receptor.
- 亚型：
IgG1
- 形态：
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
- 克隆性：
Monoclonal Antibody
- 标记物：
FITC
- 适应物种：
Human
- 保质期：
自发货之日起 12 个月
- 目录编号：
GE2
- 供应商：
伯乐生命医学产品（上海）有限公司
- 应用范围：
F
- 浓度：
IgG concentration 0.1mg/ml
- 抗体名：
Dectin-1 antibody | GE2
- 规格：
0.1 mg
Human Dectin-1 has two major (βGR-A and βGR-B) and several minor isoforms. βGR-A and βGR-B differ by the presence and absence, respectively, of a stalk region. Mouse anti Human Dectin-1 antibody, clone GE2 recognizes both major isoforms. Clone GE2 could be used to inhibit receptor function.
储存信息
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
应用
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry | ✓ | Neat | 1/10 |
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
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文献和实验Source Reference
- Willment, J.A. et al. (2005) The human beta-glucan receptor is widely expressed and functionally equivalent to murine Dectin-1 on primary cells.
Eur J Immunol. 35 (5): 1539-47.
References for Dectin-1 antibody
- Harnack, U. et al. (2011) Yeast-derived beta-(1-3),(1-6)-D-glucan induces up-regulation of CD86 on dectin-1-positive human B-lymphoma cell lines.
Anticancer Res. 31 (12): 4195-9. - Kyrmizi, I. et al. (2013) Corticosteroids block autophagy protein recruitment in Aspergillus fumigatus phagosomes via targeting dectin-1/Syk kinase signaling.
J Immunol. 191 (3): 1287-99. - Loures, F.V. et al. (2015) Recognition of Aspergillus fumigatus hyphae by human plasmacytoid dendritic cells is mediated by dectin-2 and results in formation of extracellular traps.
PLoS Pathog. 11 (2): e1004643. - Ali, M.F. et al. (2017) Canonical Stimulation of the NLRP3 Inflammasome by Fungal Antigens Links Innate and Adaptive B-Lymphocyte Responses by Modulating IL-1β and IgM Production.
Front Immunol. 8: 1504. - Kan, B. et al. (2018) Cellular metabolism constrains innate immune responses in early human ontogeny.
Nat Commun. 9 (1): 4822. - de Quaglia E Silva. J.C.et al. (2019) Involvement of the Dectin-1 Receptor upon the Effector Mechanisms of Human Phagocytic Cells against Paracoccidioides brasiliensis.
J Immunol Res. 2019: 1529189.
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Intraspinal Transplantation of Mouse and Human Neural Precursor Cells
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