Sample:
LOVO(Human) Cell Lysate at 30 ug
MCF-7(Human) Cell Lysate at 30 ug
Primary: Anti-Neurotensin Receptor 1 (bs-12002R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46 kD
Observed band size: 46 kD
- ￥1180 - 2800
- Bioss
- bs-12002R
- 2025年10月17日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-12002R |
| 英文名称 | Neurotensin Receptor 1 Rabbit pAb |
| 中文名称 | 神经降压素受体1抗体 |
| 英文别名 | High affinity levocabastine insensitive neurotensin receptor; Neurotensin receptor type 1; NT R 1; NTR; NTR1; NTRH; NTRR; NTR-1; NTSR 1; NTR1_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human NTR1/Neurotensin Receptor 1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 46 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Neurotransmission > Receptors / Channels > GPCR > Dopamine Receptors Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. Neurotensin receptor subfamily. NTSR1 sub-subfamily. |
| 功能 | Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. NTR1 has been reported in brain, pancreas, and small intestine. ESTs have been isolated from brain and colon libraries. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive Neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). Neurotensin has a wide distribution in regions of the brain and in peripheral tissues where Neuro-tensin receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o, or Gs. Alternative splicing of rat NTR2 can generate a five-transmembrane domain variant isoform that is co-expressed with the full-length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1b and TNFa in an ERK1/2- and Akt kinase-dependent manner. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Sample:
DU145(Human) Cell Lysate at 30 ug
Primary: Anti-Neurotensin Receptor 1 (bs-12002R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46 kD
Observed band size: 46 kD
DU145(Human) Cell Lysate at 30 ug
Primary: Anti-Neurotensin Receptor 1 (bs-12002R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46 kD
Observed band size: 46 kD
Sample:
Lane 1: NTSR1 KO Human 293T cell lysates
Lane 2: NTSR1 KO Human 293T cell lysates
Lane 3: Human 293T cell lysates
Primary: Anti-Neurotensin Receptor 1 (bs-12002R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46 kDa
Observed band size: 46 kDa
Lane 1: NTSR1 KO Human 293T cell lysates
Lane 2: NTSR1 KO Human 293T cell lysates
Lane 3: Human 293T cell lysates
Primary: Anti-Neurotensin Receptor 1 (bs-12002R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46 kDa
Observed band size: 46 kDa
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文献和实验该产品被引用文献
[IF={{ 6 }}] {Qiong Wang. et al. A novel androgen-independent radiotracer with dual targeting of NTSR1 and PSMA for PET/CT imaging of prostate cancer. EUR J MED CHEM. 2025 Jan;282:117050} {IHC} {Mouse}
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Neurotensin Receptor 1 Rabbit pAb(bs-12002R)-50ul/100ul/200ul
￥1180 - 2800
