FOXP3 Rabbit pAb, Cy7 conjugated(bs-10211R-Cy7)-100ul

FOXP3 Rabbit pAb, Cy7 conjugat

ed(bs-10211R-Cy7)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-10211R-Cy7
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-10211R-Cy7
    英文名称FOXP3 Rabbit pAb, Cy7 conjugated
    中文名称Cy7标记的叉头蛋白P3抗体
    英文别名Forkhead box protein P3; forkhead box P3; Scurfin; Forkhead box protein P3, C-terminally processed; Forkhead box protein P3 41 kDa form; JM2; AIID; IPEX; PIDX; XPID; DIETER; FOXP3_HUMAN;
    产品应用Flow-Cyt=0.2ug/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human FoxP3
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Cell Cycle > Cell Division > Chromatid Cohesion

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Forkhead Box > FOXP

    Immunology > Adaptive Immunity > Regulatory T Cells

    亚基Interacts with IKZF3.
    亚细胞定位Nucleus (Potential).
    翻译后修饰Acetylation on lysine residues stabilizes FOXP3 and promotes differentiation of T-cells into induced regulatory T-cells (iTregs) associated with suppressive functions. Deacetylated by SIRT1.
    相似性Contains 1 C2H2-type zinc finger.
    Contains 1 fork-head DNA-binding domain.
    功能Probable transcription factor. Plays a critical role in the control of immune response.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

     

    应用推荐稀释比例
    {Flow-Cyt}{0.2ug/Test}

     

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