Ricin B chain Rabbit pAb(bs-7141R)-50ul/100ul/200ul

Ricin B chain Rabbit pAb(bs-71

41R)-50ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-7141R
  • 2025年10月17日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-7141R
    英文名称Ricin B chain Rabbit pAb
    中文名称蓖麻毒素B链抗体
    英文别名Ricin toxin B chain; Ricinus communis(Castor bean); RCA 60; Ricin B lectin; Ricin chain B; Ricin precursor; rRNA N-glycosidase; RT B; RTB; RICI_RICCO.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 (Ricinus communis (Castor Bean plant).)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from Ricin B chain
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量29 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Other Antibodies > Plant related targets

    Epigenetics and Nuclear Signaling > DNA / RNA > Translation > Regulation

    亚基Disulfide-linked dimer of A and B chains.The B chain is composed of two domains, each domain consists of 3 homologous subdomains (alpha, beta, gamma).
    功能Ricin is highly toxic to animal cells and to a lesser extent to plant cells. The A chain acts as a glycosidase that removes a specific adenine residue from an exposed loop of the 28S rRNA (A4324 in mammals), leading to rRNA breakage. As this loop is involved in elongation factor binding, modified ribosomes are catalytically inactive and unable to support protein synthesis. The A chain can inactivate a few thousand ribosomes per minute, faster than the cell can make new ones. Therefore a single A chain molecule can kill an animal cell. The B chain binds to beta-D-galactopyranoside moieties on cell surface glycoproteins and glycolipids and facilitates the entry into the cell of the A chain; B chains are also responsible for cell agglutination (Lectin activity).
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {ICC/IF}{1:100-500}
    {IF}{1:100-500}

     

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    ¥1180 - 2800