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- bs-4778P
- 2025年10月16日
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500ug
| 产品编号 | bs-4778P |
| 英文名称 | TNFRSF8 Antibody Blocking Peptide |
| 中文名称 | CD30封闭多肽 |
| 英文别名 | CD 30; CD30; CD30 antigen; CD30L receptor; Cytokine receptor CD30; D1S166E; KI 1; Ki 1 antigen; Ki-1 antigen; KI1; Lymphocyte activation antigen CD30; TNFRSF 8; TNFRSF8; TNFRSF8; TNR8_MOUSE; Tumor Necrosis Factor Receptor Superfamily Member 8; Tumor Necrosis Factor Receptor Superfamily Member 8. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Tumor biomarkers > Receptors Cancer > Tumor immunology > CD markers Immunology > Cell Type Markers > CD > Non-lineage Immunology > Innate Immunity > Cytokines > TNF Superfamily |
| 亚基 | Interacts with TRAF1, TRAF2, TRAF3 and TRAF5. |
| 亚细胞定位 | Isoform Long: Cell membrane; Single-pass type I membrane protein. Isoform Short: Cytoplasm. |
| 组织特异性 | Detected in thymus and in activated splenocytes. |
| 翻译后修饰 | Phosphorylated on serine and tyrosine residues. |
| 相似性 | Contains 6 TNFR-Cys repeats |
| 功能 | Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
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TNFRSF8 Antibody Blocking Peptide(bs-4778P)-500ug
￥880
