PTGER3 Antibody Blocking Peptide(bs-23959P)-500ug

PTGER3 Antibody Blocking Pepti

de(bs-23959P)-500ug
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  • bs-23959P
  • 2025年10月16日
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      500ug

    产品编号bs-23959P
    英文名称PTGER3 Antibody Blocking Peptide
    中文名称前列腺素E受体3封闭多肽
    英文别名EP 3; EP3; EP3 I; EP3 II; EP3 III; EP3 IV; Ep3 prostanoid receptor; Ep3 receptor; EP3 subtype; EP3e; HGNC:9595; MGC141828; MGC141829; MGC27302; PE2R3_HUMAN; PGE receptor EP3 subtype; PGE2 R; PGE2 receptor EP3 subtype; PGE2-R; PGE2R; Pgerep3; Prostaglandin E receptor 3 (subtype EP3); Prostaglandin E receptor 3; Prostaglandin E receptor EP3 subtype 3 isoform; Prostaglandin E2 receptor; Prostaglandin e2 receptor ep3; Prostaglandin E2 receptor EP3 subtype; Prostaglandin receptor (PGE 2); Prostaglandin receptor 3, EP3, subtype; Prostanoid EP3 receptor; PTGER 3; Ptger3; Ptgerep3; Rep3; rEP3a; rEP3b.
    纯化方法HPLC
    研究领域

    Metabolism > Types of disease > Obesity

    Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR

    亚细胞定位Cell membrane; Multi-pass membrane protein.
    组织特异性Expressed in small intestine, heart, pancreas, gastric fundic mucosa, mammary artery and pulmonary vessels.
    相似性Belongs to the G-protein coupled receptor 1 family.
    功能Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

     

     

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