HINT1 Antibody Blocking Peptide(bs-10228P)-500ug

HINT1 Antibody Blocking Peptid

e(bs-10228P)-500ug
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  • bs-10228P
  • 2025年10月16日
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      500ug

    产品编号bs-10228P
    英文名称HINT1 Antibody Blocking Peptide
    中文名称组氨酸三聚体核苷结合蛋白1封闭多肽
    英文别名histidine triad nucleotide binding protein 1; Adenosine 5' monophosphoramidase; Adenosine 5'-monophosphoramidase; HINT 1; HINT-1; histidine triad nucleotide binding protein 1; histidine triad nucleotide binding protein; histidine triad nucleotide-binding protein; Histidine triad nucleotide-binding protein 1; PKCI 1; PKCI-1; PKCI1; PRKCNH1; Protein kinase C inhibitor 1; Protein kinase C interacting protein 1; Protein kinase C-interacting protein 1; HINT1_HUMAN.
    纯化方法HPLC
    研究领域

    Cancer > Oncoproteins/suppressors > Tumor suppressors

    Epigenetics and Nuclear Signaling > DNA / RNA > DNA / Nucleotides

    Epigenetics and Nuclear Signaling > Transcription > Cancer susceptibility > Tumor Suppressors

    亚基Homodimer. Interacts with CDK7.
    亚细胞定位Cytoplasm. Nucleus. Note=Interaction with CDK7 leads to a more nuclear localization.
    组织特异性Widely expressed.
    相似性Belongs to the HINT family.
    Contains 1 HIT domain.
    功能Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. This gene has been found to be a tumor suppressing gene. Several transcript variants, but only one of them protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012].

     

     

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