MMP11 Antibody Blocking Peptide(bs-1853P)-500ug

MMP11 Antibody Blocking Peptid

e(bs-1853P)-500ug
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  • bs-1853P
  • 2025年10月16日
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      500ug

    产品编号bs-1853P
    英文名称MMP11 Antibody Blocking Peptide
    中文名称基质金属蛋白酶11封闭多肽
    英文别名matrix metalloproteinase 11; Stromelysin-3; SL-3; Matrix metalloproteinase-11; MMP11; MMP 11; MMP-11; SL 3; SL3; ST 3; ST3; STMY 3; STMY3; Stromelysin 3; Stromelysin 3 precursor; Stromelysin III; Stromelysin3; StromelysinIII. MMP11_HUMAN; stromelysin-3 preproprotein.
    纯化方法HPLC
    研究领域

    Cancer > Invasion/microenvironment > Angiogenesis > ECM enzymes > MMPs

    Cancer > Invasion/microenvironment > ECM > Extracellular matrix > TIMPs

    Cardiovascular > Angiogenesis > Adhesion / ECM > Matrix Metalloproteinases > MMP

    Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Metalloprotease > MMPs

    Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Enzymes > MMP

    亚基Secreted, extracellular space, extracellular matrix (Probable).
    亚细胞定位Secreted, extracellular space, extracellular matrix (Probable).
    组织特异性Specifically expressed in stromal cells of breast carcinomas.
    翻译后修饰The precursor is cleaved by a furin endopeptidase.
    相似性Belongs to the peptidase M10A family.
    Contains 4 hemopexin-like domains.
    功能May play an important role in the progression of epithelial malignancies.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008].

     

     

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