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- Bioss
- bs-9524P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-9524P |
| 英文名称 | PIGA Antibody Blocking Peptide |
| 中文名称 | 红细胞磷脂酰肌醇聚糖A封闭多肽 |
| 英文别名 | GlcNAc PI synthesis protein; GlcNAc-PI synthesis protein; GPI3; Phosphatidylinositol glycan anchor biosynthesis class A; phosphatidylinositol glycan anchor biosynthesis, class A (paroxysmal nocturnal hemoglobinuria); Phosphatidylinositol N-acetylglucosaminyltransferase subunit A; PIG A; PIG-A; PIGA_HUMAN; Phosphatidylinositol-glycan biosynthesis class A protein; PIG-A. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Blood > Erythrocytes |
| 亚基 | Associates with PIGC, PIGH, PIGP, PIGQ and DPM2. The latter is not essential for activity. Interacts directly with PIGY. |
| 亚细胞定位 | Endoplasmic reticulum membrane; Single-pass membrane protein |
| 相似性 | Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. |
| 功能 | Necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | PIGA belongs to the glycosyltransferase 1 family and is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis. Defects in PIGA are the cause of paroxysmal nocturnal hemoglobinuria (PNH) which is an acquired hemolytic blood disorder characterized by chronic hemolysis with hemoglobinuria, increased tendency to venous thrombosis, and variable degrees of bone marrow failure. |
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PIGA Antibody Blocking Peptide(bs-9524P)-500ug
￥880
