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- bs-3791P
- 2025年10月16日
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500ug
| 产品编号 | bs-3791P |
| 英文名称 | RAE1 Antibody Blocking Peptide |
| 中文名称 | mRNA结合蛋白封闭多肽 |
| 英文别名 | RAE-1; MIG 14; MIG14; Mnrp 41; Mnrp41; mRNA associated protein mrnp 41; mRNA binding protein 41 kD; mRNA export protein; MRNP 41; MRNP41; RAE 1; RAE1 (RNA export 1 S.pombe) homolog; RAE1 homolog; Rae1 protein homolog; RAE1 RNA export 1 homolog; RNA export 1; RNA export 1 homolog; Homolog of yeast Rae1 mRNA associated protein of 41 kDa. RAE1L_HUMAN |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Cell Division > Spindle Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing Signal Transduction > Protein Trafficking > Nuclear Import / Export Tags & Cell Markers > Subcellular Markers > Nucleus > Nuclear Pore |
| 亚基 | Interacts with NUP98. |
| 亚细胞定位 | Cytoplasm. Nucleus. |
| 相似性 | Belongs to the WD repeat rae1 family. Contains 7 WD repeats. |
| 功能 | Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Mutations in Rae1 and Gle2(Saccharomyces cerevisae homolog) genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Depletion of Rae1 from extracts or cells severely inhibits mitotic spindle assembly. Alternatively spliced transcript variants encoding the same protein have been found for this gene. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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