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- bs-9431P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-9431P |
| 英文名称 | KCTD5 Antibody Blocking Peptide |
| 中文名称 | 钾离子通道四聚体结构域蛋白5封闭多肽 |
| 英文别名 | BTB/POZ domain-containing protein KCTD5; FLJ20040; KCTD5; KCTD5_HUMAN; Potassium channel tetramerisation domain containing 5. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > Ubiquitin E3 Enzymes > RING Finger E3 Ligase |
| 亚基 | Homopentamer. Interacts (via C-terminus) with GRASP55/GORASP2. Interacts with CUL3 and with ubiquitinated proteins. Interacts with adeno-associated virus 2 (AAV-2) REP proteins. |
| 亚细胞定位 | Cytoplasm, cytosol. Nucleus. Note=Predominantly cytoplasmic, translocated to the nucleus upon interaction with Rep proteins. |
| 相似性 | Contains 1 BTB (POZ) domain. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KCTD5 (potassium channel tetramerisation domain containing 5) is a 234 amino acid protein that localizes predominantly in the cytoplasm but translocates to the nucleus upon interaction with REP proteins. Existing as a homopentamer and consisting of one BTB (POZ) domain, KCTD5 associates with GRASP55, CUL-3 and ubiquitinated proteins. Interaction with CUL-3 suggests KCTD5 functions as a substrate adapter protein in some E3 ligase complexes. |
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KCTD5 Antibody Blocking Peptide(bs-9431P)-500ug
￥880
