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- 2025年10月16日
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500ug
| 产品编号 | bs-20838P |
| 英文名称 | LY6E Antibody Blocking Peptide |
| 中文名称 | T淋巴细胞激活蛋白封闭多肽 |
| 英文别名 | Ly 6E; Ly6A.2; Ly6A/E; Ly6E.1; Lymphocyte antigen 6 complex locus A; Lymphocyte antigen 6 complex locus E; Lymphocyte antigen 6E; OTTHUMP00000227386; OTTHUMP00000227387; OTTHUMP00000227407; OTTHUMP00000227411; OTTHUMP00000227413; OTTHUMP00000227414; OTTHUMP00000227415; OTTHUMP00000227416; OTTHUMP00000227418; OTTHUMP00000227419; Retinoic acid induced gene E; Retinoic acid induced gene E protein; RIG E; RIGE; SCA 2; Sca1; Sca2; Stem cell antigen 1; Stem cell antigen 2; T cell activating protein; TAP; Thymic shared antigen 1; TSA 1; TSA1 |
| 纯化方法 | HPLC |
| 组织特异性 | Widely expressed, predominantly in liver, kidney, ovary, spleen and peripheral blood Leukocytes. |
| 相似性 | Contains 1 UPAR/Ly6 domain. |
| 功能 | GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR) signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation (By similarity). Restricts the entry of human coronaviruses, including SARS-CoV, MERS-CoV and SARS-CoV-2, by interfering with spike protein-mediated membrane fusion (PubMed:32641482). Also plays an essential role in placenta formation by acting as the main receptor for syncytin-A (SynA). Therefore, participates in the normal fusion of syncytiotrophoblast layer I (SynT-I) and in the proper morphogenesis of both fetal and maternal vasculatures within the placenta. May also act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene belongs to the human Ly6 gene family and encodes a glycosylphosphatidyl-inositol (GPI)-anchored cell surface protein. The protein plays an important role in T cell physiology, oncogenesis and immunological regulation. The protein is also involved in modulation of viral infection by coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-2. [provided by RefSeq, Aug 2021] |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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