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- Bioss
- bs-23975P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-23975P |
| 英文名称 | CRHR2 Antibody Blocking Peptide |
| 中文名称 | 促肾上腺皮质释放激素受体2封闭多肽 |
| 英文别名 | Corticotropin releasing hormone receptor 2; Corticotropin-releasing factor receptor 2; Corticotropin-releasing hormone receptor 2; CRF 2; CRF 2R; CRF R2; CRF-R-2; CRF-R2; CRF2; CRF2R; CRFR 2; CRFR-2; CRFR2; CRFR2_HUMAN; CRH 2R; CRH R2; CRH-R-2; CRH-R2; CRH2R; CRHR 2; CRHR2. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Endocrine system > Hypothalamic pituitary adrenal axis Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR |
| 亚基 | Interacts (via N-terminal extracellular domain) with CRF, UCN, UCN2 and UCN3. Has highest affinity for UCN, and considerably lower affinity for CRF, UNC2 and UCN3. |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 相似性 | Belongs to the G-protein coupled receptor 2 family. |
| 功能 | This is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. Also binds to urocortin I, II and III. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jan 2011] |
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CRHR2 Antibody Blocking Peptide(bs-23975P)-500ug
￥880
