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500ug
| 产品编号 | bs-9407P |
| 英文名称 | OIF Antibody Blocking Peptide |
| 中文名称 | 骨诱导因子封闭多肽 |
| 英文别名 | Corneal keratan sulfate proteoglycan; MIME_HUMAN; mimecan; Mimecan proteoglycan; OG; OGN; OIF; osteoglycin; osteoinductive factor; SLRR3A. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Cell differentiation Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > Structures > Bone |
| 亚细胞定位 | Secreted, extracellular space, extracellular matrix. |
| 组织特异性 | Bone. |
| 翻译后修饰 | N- and O-glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan. |
| 相似性 | Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily. Contains 7 LRR (leucine-rich) repeats. |
| 功能 | Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The small leucine-rich proteoglycan (SLRP) family of proteins contains various proteins such as Decorin, Biglycan, Fibromodulin, Keratocan, Lumican, Osteoadherin and Osteoglycin. These proteins all have similar functions as they all mediate extracellular matrix organization and act as binding partners of TGF beta. Osteoglycin, which also may be designated osteoinductive factor (OIF), is a secreted protein detected in bone tissues. Osteoglycin induces the formation of bone in conjunction with either TGF-beta-1 or TGF-beta-2. The precursor form of the OGN gene product, designated Mimecan, is subject to in situ proteolytic cleavage to yield the mature Osteoglycin. |
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OIF Antibody Blocking Peptide(bs-9407P)-500ug
¥880







