OIF Antibody Blocking Peptide(bs-9407P)-500ug

OIF Antibody Blocking Peptide(

bs-9407P)-500ug
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  • bs-9407P
  • 2025年10月16日
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      500ug

    产品编号bs-9407P
    英文名称OIF Antibody Blocking Peptide
    中文名称骨诱导因子封闭多肽
    英文别名Corneal keratan sulfate proteoglycan; MIME_HUMAN; mimecan; Mimecan proteoglycan; OG; OGN; OIF; osteoglycin; osteoinductive factor; SLRR3A.
    纯化方法HPLC
    研究领域

    Cell Biology > Cell Cycle > Cell differentiation

    Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > Structures > Bone

    亚细胞定位Secreted, extracellular space, extracellular matrix.
    组织特异性Bone.
    翻译后修饰N- and O-glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
    相似性Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
    Contains 7 LRR (leucine-rich) repeats.
    功能Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The small leucine-rich proteoglycan (SLRP) family of proteins contains various proteins such as Decorin, Biglycan, Fibromodulin, Keratocan, Lumican, Osteoadherin and Osteoglycin. These proteins all have similar functions as they all mediate extracellular matrix organization and act as binding partners of TGF beta. Osteoglycin, which also may be designated osteoinductive factor (OIF), is a secreted protein detected in bone tissues. Osteoglycin induces the formation of bone in conjunction with either TGF-beta-1 or TGF-beta-2. The precursor form of the OGN gene product, designated Mimecan, is subject to in situ proteolytic cleavage to yield the mature Osteoglycin.

     

     

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