- ￥880
- Bioss
- bs-18568P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-18568P |
| 英文名称 | ZSWIM7 Antibody Blocking Peptide |
| 中文名称 | ZSWIM7蛋白封闭多肽 |
| 英文别名 | SWIM domain-containing and Srs2-interacting protein 1 homolog; SWIM domain-containing Srs2-interacting protein 1; SWIM-type zinc finger domain-containing protein 7; SWS1; Zinc finger SWIM domain-containing protein 7; Zinc finger, SWIM-type containing 7; zswim7; ZSWM7_HUMAN. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Nucleus. |
| 相似性 | Belongs to the SWS1 family. Contains 1 SWIM-type zinc finger. |
| 功能 | Involved in early stages of the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ZSWIM7 is a 140 amino acid nuclear protein that contains a SWIM-type zinc finger and belongs to the SWS1 family. ZSWIM7 interacts with Rad51D, and plays a role in the early stages of the homologous recombination repair (HRR) pathway that occurs during double-stranded DNA breaks. The gene encoding ZSWIM7 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. |
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ZSWIM7 Antibody Blocking Peptide(bs-18568P)-500ug
￥880
