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500ug
| 产品编号 | bs-9372P |
| 英文名称 | PGGT1B Antibody Blocking Peptide |
| 中文名称 | 香叶烯基转移酶1β封闭多肽 |
| 英文别名 | PGGT1B; GGTase-I beta; GGTase-1 beta; BGGI; Geranylgeranyl transferase type I subunit beta; Geranylgeranyl transferase type-1 subunit beta; GGTase-I-beta; GGTI; PGGT1B; PGTB1_HUMAN; Type I protein geranyl-geranyltransferase subunit beta; |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies |
| 亚基 | Heterodimer of an alpha and a beta subunit. |
| 相似性 | Belongs to the protein prenyltransferase subunit beta family. Contains 4 PFTB repeats. |
| 功能 | Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Acts on the Rac1, Rac2, Rap1A and Rap1B proteins. The beta subunit is responsible for peptide-binding. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010] |
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PGGT1B Antibody Blocking Peptide(bs-9372P)-500ug
¥880







