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500ug
| 产品编号 | bs-7904P |
| 英文名称 | AKAP6 Antibody Blocking Peptide |
| 中文名称 | 蛋白激酶A锚定蛋白6封闭多肽 |
| 英文别名 | A kinase (PRKA) anchor protein 6; A kinase anchor protein 100; A kinase anchor protein 100 kDa; A kinase anchor protein 6; ADAP 100; ADAP 6; ADAP100; ADAP6; AKAP 100; AKAP 6; AKAP100; Human A kinase anchor protein AKAP100; KIAA0311; mAKAP; PRKA 6; PRKA6; Protein kinase A anchoring protein 6; AKAP6_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Kinases/Phosphatases |
| 亚基 | Interacts with RII subunit of PKA, phosphatase 2B (calcineurin) and AKAP79. |
| 亚细胞定位 | Sarcoplasmic reticulum. Nucleus membrane. Note=In heart muscle. Participation of multiple targeting signals allow correct intracellular targeting. These may be repeated motifs rich in basic and hydrophobic amino acids, palmitoylated/myristoylated motifs or alternatively splice targeting sequences. |
| 组织特异性 | Highly expressed in cardiac and skeletal muscle, followed by brain. |
| 相似性 | Contains 2 spectrin repeats. |
| 功能 | Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the nuclear membrane or sarcoplasmic reticulum. May act as an adapter for assembling multiprotein complexes. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The A Kinase Anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP6 is a member of the AKAP family. It is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum. |
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AKAP6 Antibody Blocking Peptide(bs-7904P)-500ug
¥880







