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- Bioss
- bs-20573P
- 2025年10月16日
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500ug
| 产品编号 | bs-20573P |
| 英文名称 | FOXC1 Antibody Blocking Peptide |
| 中文名称 | 叉头相关转录因子3/FOXC1封闭多肽 |
| 英文别名 | ARA; FKH L7; FKHL 7; FKHL7; Forkhead (Drosophila) like 7; Forkhead; forkhead box C1; Forkhead box protein C1; Forkhead drosophila homolog like 7; Forkhead like 7; Forkhead related activator 3; Forkhead related protein FKHL7; Forkhead related transcription factor 3; Forkhead-related protein FKHL7; Forkhead-related transcription factor 3; FOX C1; FOXC 1; FOXC1; FOXC1_HUMAN; FREAC 3; FREAC-3; FREAC3; homolog-like 7; IGDA; IHG 1; IHG1; IRID 1; IRID1; Iridogoniodysgenesis type 1; Myeloid factor delta. |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Organogenesis > Excretory system development > Kidney development Epigenetics and Nuclear Signaling > Transcription > Domain Families > Forkhead Box Epigenetics and Nuclear Signaling > Transcription > Domain Families > Forkhead Box > FOXC Epigenetics and Nuclear Signaling > Transcription > Transcription Factors |
| 亚基 | Monomer. |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Expressed in all tissues and cell lines examined. |
| 相似性 | Contains 1 fork-head DNA-binding domain. |
| 功能 | Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees.Involvement in disease; Defects in FOXC1 are the cause of Axenfeld-Rieger syndrome type 3 (RIEG3); also known as Axenfeld-Rieger syndrome (ARS) or Axenfeld syndrome or Axenfeld anomaly. It is characterized by posterior corneal embryotoxon, prominent Schwalbe line and iris adhesion to the Schwalbe line. Other features may be hypertelorism (wide spacing of the eyes), hypoplasia of the malar bones, congenital absence of some teeth and mental retardation. When associated with tooth anomalies, the disorder is known as Rieger syndrome. Glaucoma is a progressive blinding condition that occurs in approximately half of patients with Axenfeld-Rieger malformations. |
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FOXC1 Antibody Blocking Peptide(bs-20573P)-500ug
￥880
