- ￥880
- Bioss
- bs-11331P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11331P |
| 英文名称 | EOMES Antibody Blocking Peptide |
| 中文名称 | 脱中胚蛋白封闭多肽 |
| 英文别名 | Eomes; EOMES_HUMAN; Eomesodermin; Eomesodermin homolog; t box brain 2; T-box brain protein 2; T-brain-2; Tbr 2; TBR-2. |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Lineage specification > Trophectoderm Developmental Biology > Reproduction > Germ cell markers Neuroscience > Cell Type Marker > Neuron marker > Soma marker Neuroscience > Neurology process > Neural Signal Transduction Neuroscience > Neurology process > Neurogenesis Stem Cells > Germline Stem Cells > Embryonic Germ Cells Stem Cells > Neural Stem Cells > Intracellular |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Expressed in CD8+ T-cells. |
| 相似性 | Contains 1 T-box DNA-binding domain. |
| 功能 | Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | EOMES (eomesodermin homolog), also known as TBR2 (T-box-brain2), is the 686 amino acid human homolog of the mouse Eomes protein that contains one T-box DNA binding domain. Genes that contain T-box domains encode proteins that function as transcription factors and are often involved in the regulation of various developmental events. Localized to the nucleus and expressed in the developing brain, EOMES is thought to be involved in neuronal migration and division and may play a role in trophoblast development and gastrulation. Silencing of the EOMES gene can cause mutated or arrested development and may lead to microcephaly disorders which are characterized by reduced head circumference and a malformed brain. |
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EOMES Antibody Blocking Peptide(bs-11331P)-500ug
￥880
