ANKRD54 Antibody Blocking Peptide(bs-20549P)-500ug

ANKRD54 Antibody Blocking Pept

ide(bs-20549P)-500ug
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  • ¥880
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  • bs-20549P
  • 2025年10月16日
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      500ug

    产品编号bs-20549P
    英文名称ANKRD54 Antibody Blocking Peptide
    中文名称锚蛋白重复域54封闭多肽
    英文别名Ankrd54; ankyrin repeat domain 54; ankyrin repeat domain 54; Ankyrin repeat domain-containing protein 54; ANR54_HUMAN; LIAR.
    纯化方法HPLC
    亚基Interacts (via ankyrin repeat region) with LYN (via SH3-domain) in an activation-independent status of LYN (By similarity). Forms a multiprotein complex with LYN and HCLS1. Interacts with TSN2, VAV1, DBNL AND LASP1.
    亚细胞定位Nucleus. Cytoplasm. Midbody. Note=Shuttles between nucleus and cytoplasm during the cell cycle. EPO stimulation induces nuclear accumulation.
    相似性Contains 8 ANK repeats.
    Contains 1 EF-hand domain.
    功能Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料ANKRD5 is a 776 amino acid protein that contains one calcium-binding EF-hand domain and 8 ankyrin repeats. The gene encoding ANKRD5 maps to chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.

     

     

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