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- Bioss
- bs-14301P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-14301P |
| 英文名称 | DGKZ Antibody Blocking Peptide |
| 中文名称 | 甘油二酯激酶ζ/DGK-ζ封闭多肽 |
| 英文别名 | DAG kinase zeta; DAGK5; DAGK5 PEN; DAGK6; DGK ZETA; DGK-zeta; Dgkz; DGKZ_HUMAN; Diacylglycerol kinase zeta; Diglyceride kinase zeta; hDGKzeta. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Heart > Hypertrophy Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > PKC Signal Transduction > Signaling Pathway > Lipid Signaling |
| 亚细胞定位 | Cytoplasm. Nucleus. Cell membrane. |
| 组织特异性 | Highest levels in brain, and substantial levels in skeletal muscle, heart, and pancreas. Isoform 1 is predominantly expressed in muscle. |
| 翻译后修饰 | Phosphorylation of the MARCKS homology domain by PKC reduces nuclear accumulation of DGK-zeta. |
| 相似性 | Belongs to the eukaryotic diacylglycerol kinase family. Contains 2 ANK repeats. Contains 1 DAGKc domain. Contains 2 phorbol-ester/DAG-type zinc fingers. |
| 功能 | Displays a strong preference for 1,2-diacylglycerols over 1,3-diacylglycerols, but lacks substrate specificity among molecular species of long chain diacylglycerols. Isoform 2 but not isoform 1 regulates RASGRP1 activity. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2010] |
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DGKZ Antibody Blocking Peptide(bs-14301P)-500ug
￥880
