Cyclin B3 Antibody Blocking Peptide(bs-7884P)-500ug

Cyclin B3 Antibody Blocking Pe

ptide(bs-7884P)-500ug
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  • bs-7884P
  • 2025年10月16日
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      500ug

    产品编号bs-7884P
    英文名称Cyclin B3 Antibody Blocking Peptide
    中文名称周期素B3封闭多肽
    英文别名CCNB 3; CCNB3; CYCB3; G2/mitotic specific cyclin B3.
    纯化方法HPLC
    亚基Interacts with CDK2 kinase.
    亚细胞定位Nucleus.
    组织特异性Testis specific. In testis, it is expressed indeveloping germ cells, but not in Leydig cells. Weakly or notexpressed in other tissues.
    翻译后修饰Ubiquitinated (Probable). Ubiquitination leads to itsdegradation during anaphase entry, after degradation of CCNB1.
    相似性Belongs to the cyclin family. Cyclin AB subfamily.
    功能Cyclins are positive regulatory subunits of thecyclin-dependent kinases (CDKs), and thereby play an essential rolein the control of the cell cycle, notably via their destructionduring cell division. Its tissue specificity suggest that it may berequired during early meiotic prophase I.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene belongs to the highlyconserved cyclin family, whose members are characterized by adramatic periodicity in protein abundance through the cell cycle.Cyclins function as positive regulators of cyclin-dependent kinases(CDKs), and thereby play an essential role in the control of thecell cycle. Different cyclins exhibit distinct expression anddegradation patterns, which contribute to the temporal coordinationof each mitotic event. Studies of similar genes in chicken anddrosophila suggest that this cyclin may associate with CDC2 andCDK2 kinases, and may be required for proper spindle reorganizationand restoration of the interphase nucleus. Alternatively splicedtranscript variants encoding different isoforms have been describedfor this gene.

     

     

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