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- 技术资料
- 规格:
500ug
| 产品编号 | bs-7884P |
| 英文名称 | Cyclin B3 Antibody Blocking Peptide |
| 中文名称 | 周期素B3封闭多肽 |
| 英文别名 | CCNB 3; CCNB3; CYCB3; G2/mitotic specific cyclin B3. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with CDK2 kinase. |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Testis specific. In testis, it is expressed indeveloping germ cells, but not in Leydig cells. Weakly or notexpressed in other tissues. |
| 翻译后修饰 | Ubiquitinated (Probable). Ubiquitination leads to itsdegradation during anaphase entry, after degradation of CCNB1. |
| 相似性 | Belongs to the cyclin family. Cyclin AB subfamily. |
| 功能 | Cyclins are positive regulatory subunits of thecyclin-dependent kinases (CDKs), and thereby play an essential rolein the control of the cell cycle, notably via their destructionduring cell division. Its tissue specificity suggest that it may berequired during early meiotic prophase I. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene belongs to the highlyconserved cyclin family, whose members are characterized by adramatic periodicity in protein abundance through the cell cycle.Cyclins function as positive regulators of cyclin-dependent kinases(CDKs), and thereby play an essential role in the control of thecell cycle. Different cyclins exhibit distinct expression anddegradation patterns, which contribute to the temporal coordinationof each mitotic event. Studies of similar genes in chicken anddrosophila suggest that this cyclin may associate with CDC2 andCDK2 kinases, and may be required for proper spindle reorganizationand restoration of the interphase nucleus. Alternatively splicedtranscript variants encoding different isoforms have been describedfor this gene. |
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Cyclin B3 Antibody Blocking Peptide(bs-7884P)-500ug
¥880








