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- Bioss
- bs-7871P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-7871P |
| 英文名称 | NEU4 Antibody Blocking Peptide |
| 中文名称 | 神经氨酸酶4封闭多肽 |
| 英文别名 | N acetyl alpha neuraminidase 4; Neuraminidase 4; Sialidase 4; NEUR4_HUMAN. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Isoform 1: Membrane; Peripheral membrane protein. Isoform 2: Lysosome lumen. |
| 组织特异性 | Ubiquitous with higher expression in heart, skeletal muscle, liver and placenta. |
| 翻译后修饰 | According to PubMed:15213228, phosphorylation of mannose residues may ensure efficient transport of isoform 2 to the lysosomes via the mannose 6-phosphate receptor. Isoform 2 is glycosylated (PubMed:15213228). |
| 相似性 | Belongs to the glycosyl hydrolase 33 family. Contains 3 BNR repeats. |
| 功能 | May function in lysosomal catabolism of sialylated glycoconjugates. Has sialidase activity towards synthetic substrates, such as 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid (4-MU-NANA or 4MU-NeuAc). Has a broad substrate specificity being active on glycoproteins, oligosaccharides and sialylated glycolipids. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | NEU4 belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. |
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NEU4 Antibody Blocking Peptide(bs-7871P)-500ug
￥880
