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- Bioss
- bs-7865P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-7865P |
| 英文名称 | GPSM1 Antibody Blocking Peptide |
| 中文名称 | G蛋白信号调节蛋白1封闭多肽 |
| 英文别名 | Activator of G-protein signaling 3; AGS3; AGS3 homolog; C10a; G protein signaling modulator 1 (AGS3 like, C. elegans); G-protein-signaling modulator 1; GPSM1; GPSM1_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > DNA Synthesis Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing |
| 亚基 | Interacts with GNAI1, GNAI2 and GNAI3 preferentially in their GDP-bound state. May also interact with GNAO1. Interacts with STK11/LKB1 and MACF1 (By similarity). Interacts with INSC/inscuteable and FRMPD1. |
| 亚细胞定位 | Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. |
| 组织特异性 | Expressed in intestinal cells. |
| 翻译后修饰 | Phosphorylation regulates interaction with G(i/o) alpha. |
| 相似性 | Belongs to the GPSM family.
Contains 4 GoLoco domains. Contains 9 TPR repeats. |
| 功能 | Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction. |
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GPSM1 Antibody Blocking Peptide(bs-7865P)-500ug
￥880
