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CSNK1D Antibody Blocking Pepti

de(bs-7607P)-500ug
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  • 2025年10月16日
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      500ug

    产品编号bs-7607P
    英文名称CSNK1D Antibody Blocking Peptide
    中文名称酪蛋白激酶δ1封闭多肽
    英文别名Casein kinase I delta isoform; Casein Kinase 1 delta; Casein kinase I isoform delta; CKI delta; CKI-delta; CKId; CSNK 1D; CSNK1D; HCKID; KC1D_HUMAN; Protein kinase CK1 delta; Casein Kinase Iδ; Casein Kinase-Iδ; Casein Kinase I δ.
    纯化方法HPLC
    研究领域

    Cell Biology > Apoptosis > Intracellular > p53 Pathway

    Cell Biology > Cell Cycle > Cell Cycle Inhibitors > p53

    Neuroscience > Neurology process > Neurodegenerative disease > Alzheimer's disease > Tangles & Tau

    Neuroscience > Neurotransmission > Intracellular Signaling > Kinases

    Stem Cells > Signaling Pathways > Wnt > Cytoplasmic

    亚细胞定位Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, perinuclear region. Cell membrane. Cytoplasm, cytoskeleton, spindle. Golgi apparatus.
    组织特异性Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. However, kinase activity is not uniform, with highest kinase activity in splenocytes. In blood, highly expressed in hemopoietic cells and mature granulocytes. Also found in monocytes and lymphocytes.
    翻译后修饰Autophosphorylated on serine and threonine residues; this autophosphorylation represses activity. Reactivated by phosphatase-mediated dephosphorylation.
    相似性Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
    Contains 1 protein kinase domain.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm.Tissue specificity: Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. In blood, highly expressed in hemopoietic cells and mature granulocytes. Also found in monocytes and lymphocytes.

     

     

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    CSNK1D Antibody Blocking Peptide(bs-7607P)-500ug
    ¥880