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500ug
| 产品编号 | bs-7860P |
| 英文名称 | DLL3 Antibody Blocking Peptide |
| 中文名称 | Notch信号通路Delta样配体3封闭多肽 |
| 英文别名 | Delta Drosophila like 3; Delta like 3 Drosophila; Delta like 3 homolog Drosophila; Delta like 3 protein; Delta like protein 3 precursor; Delta3; Drosophila Delta homolog 3; SCDO1; Spondylocostal dysostosis autosomal recessive.DLL3_HUMAN |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Cell differentiation Developmental Biology > Embryogenesis > Somatogenesis Epigenetics and Nuclear Signaling > Cell cycle > Cell Differentiation Neuroscience > Neurology process > Notch Pathway |
| 亚基 | Can bind and activate Notch-1 or another Notch receptor (Probable). |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein (Probable). |
| 组织特异性 | Predominantly expressed in the neuroectoderm and paraxial mesoderm during embryogenesis. |
| 翻译后修饰 | Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. |
| 相似性 | Contains 1 DSL domain. Contains 6 EGF-like domains. |
| 功能 | Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Delta-like 3 (DLL3) is a transmembrane Delta-like protein that inhibits primary neurogenesis. It may be required to divert neurons along a specific differentiation pathway and plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 is one of five DSL proteins that bind to the Notch receptor and activates Notch signaling. |
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DLL3 Antibody Blocking Peptide(bs-7860P)-500ug
¥880







