- ￥880
- Bioss
- bs-7845P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-7845P |
| 英文名称 | RASSF7 Antibody Blocking Peptide |
| 中文名称 | RAS家族关联结构域蛋白7封闭多肽 |
| 英文别名 | C11orf13; Chromosome 11 open reading frame 13; HRAS1; HRAS1 related cluster 1; HRAS1 related cluster protein 1; HRC1; MGC126069; Ras association (RalGDS/AF 6) domain family (N terminal) member 7; Ras association (RalGDS/AF 6) domain family 7; Ras association domain containing protein 7; RASSF 7; RASF7_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Cell Division > Spindle Epigenetics and Nuclear Signaling > Chromosome Structure > Chromatin assembly Tags & Cell Markers > Subcellular Markers > Organelles > Centrosome |
| 亚基 | Interacts with MAP2K7 and GTP-bound NRAS. |
| 亚细胞定位 | Cytoplasm, cytoskeleton, centrosome. Note=Colocalizes with gamma-tubulin. |
| 翻译后修饰 | Polyubiquitinated and degraded by the proteasome upon prolonged stress stimuli. |
| 相似性 | Contains 1 Ras-associating domain. |
| 功能 | Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | RASSF7 contains 1 Ras-associating domain. It is a centrosome-associated protein required to form a spindle and complete mitosis in the neural tube. There are two isoforms. |
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RASSF7 Antibody Blocking Peptide(bs-7845P)-500ug
￥880
