- ￥880
- Bioss
- bs-9201P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-9201P |
| 英文名称 | IGSF11 Antibody Blocking Peptide |
| 中文名称 | 大脑和睾丸特异性免疫球蛋白超家族成员11封闭多肽 |
| 英文别名 | brain and testis specific immunoglobin superfamily protein; BTIGSF; CXADR like 1; CXADRL1; Igsf13; immunoglobulin superfamily member 11; Immunoglobulin superfamily member 11 precursor; MGC35227; V set and immunoglobulin domain containing 3; V set and immunoglobulin domain containing protein 3; VSIG3; IGS11_HUMAN. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cell Membrane, Single-pass type I membrane protein. |
| 组织特异性 | bundantly expressed in testis and ovary and to a lower extent in brain, kidney and skeletal muscle. |
| 翻译后修饰 | N-glycosylated (By similarity). |
| 相似性 | Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
| 功能 | Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cell–cell interactions are also thought to be important for neuronal cell interactions, such as neuron–neuron or neuron–glia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be involved interactions between Sertoli cells and spermatocytes, which are important associations during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy. |
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IGSF11 Antibody Blocking Peptide(bs-9201P)-500ug
￥880
