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ATG9B Antibody Blocking Peptid

e(bs-4011P)-500ug
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  • 2025年10月16日
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      500ug

    产品编号bs-4011P
    英文名称ATG9B Antibody Blocking Peptide
    中文名称自噬相关蛋白9B封闭多肽
    英文别名APG9 like 2; APG9-like 2; APG9L2; Apgdc2; ATG9 autophagy related 9 homolog B; Atg9b; Autophagy related protein 9B; Autophagy-related protein 9B; eONE; Gm574; Nitric oxide synthase 3 overlapping antisense gene protein; Nitric oxide synthase 3-overlapping antisense gene protein; NOS3AS; Protein sONE; SONE; Apg912.
    纯化方法HPLC
    研究领域

    Cancer > Cell Death > Autophagy > APG gene products

    Cancer > Cell Death > Autophagy > Signal Transduction

    Cancer > Signal transduction > Autophagy

    Cardiovascular > Heart > Autophagy > APG gene products

    Metabolism > Pathways and Processes > Metabolism processes > Autophagy and mitophagy

    Metabolism > Pathways and Processes > Metabolism processes > Autophagy and mitophagy > APG gene products

    亚细胞定位Cytoplasmic vesicle ?autophagosome membrane; Multi-pass membrane protein. Note: Under amino acid starvation or rapamycin treatment, redistributes from a juxtanuclear clustered pool to a dispersed peripheral cytosolic pool. The starvation-induced redistribution depends on ULK1 and ATG13.
    组织特异性Highly expressed in placenta (trophoblast cells) and pituitary gland. Not expressed in vascular endothelial.
    相似性Belongs to the ATG9 family.
    功能Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene functions in the regulation of autophagy, a lysosomal degradation pathway. This gene also functions as an antisense transcript in the posttranscriptional regulation of the endothelial nitric oxide synthase 3 gene, which has 3' overlap with this gene on the opposite strand. Mutations in this gene and disruption of the autophagy process have been associated with multiple cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]

     

     

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