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- bs-7805P
- 2025年10月16日
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500ug
| 产品编号 | bs-7805P |
| 英文名称 | KIFC1 Antibody Blocking Peptide |
| 中文名称 | 驱动蛋白家族成员C1封闭多肽 |
| 英文别名 | HSET KNSL2; KIF C1; KIFC 1; KIFC1; KIFC1_HUMAN; Kinesin family member C1; Kinesin like 2; Kinesin like protein 2; Kinesin like protein KIFC1; Kinesin related protein HSET; Kinesin-like protein 2; Kinesin-like protein KIFC1; Kinesin-related protein HSET; KNSL 2; KNSL2; Mitotic kinesin like protein 2; MKLP 2; MKLP2; RAB6 KIFL; Rabkinesin 6. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Cell Division > Other cell division antibodies Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Motor Proteins > Kinesin Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Motor Proteins > Kinesin-like |
| 亚基 | Binds NUBP1 and NUBP2. Interacts with PPP1R42 (By similarity). |
| 亚细胞定位 | Nucleus. Cytoplasm; cytoskeleton; centrosome. Cytoplasm; cytoskeleton; spindle. Early endosome. Associated with nucleus during interphase, centrosomes in early and spindle in later mitosis. |
| 相似性 | Belongs to the kinesin-like protein family. NCD subfamily.
Contains 1 kinesin-motor domain. |
| 功能 | Minus end-directed microtubule-dependent motor required for bipolar spindle formation. May contribute to movement of early endocytic vesicles. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIFC1 is a 673 amino acid protein that belongs to the kinesin-like family of proteins. KIFC1 localizes to the nucleus and contains a C-terminal kinesin-motor domain. Functioning as a minus-end directed microtubule-dependent motor, KIFC1 works together with NuMA and cytoplasmic Dynein to organize microtubule minus ends at spindle poles. HeLa cells deficient in KIFC1 exhibit multipolar mitotic spindles, suggesting that KIFC1 is essential for bipolar spindle formation. |
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KIFC1 Antibody Blocking Peptide(bs-7805P)-500ug
￥880
