- ￥880
- Bioss
- bs-9181P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-9181P |
| 英文名称 | Repetin Antibody Blocking Peptide |
| 中文名称 | 中间丝相关蛋白封闭多肽 |
| 英文别名 | Intermediate filament associated protein; RPTN; RPTN_HUMAN. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Secreted; extracellular space; extracellular matrix. |
| 组织特异性 | Repetin is a multifunctional epidermal matrix protein involved in the cornified cell envelope formation. It reversibly binds calcium. Expression is scattered in the normal epidermis but strong in the acrosyringium, the inner hair root sheat and in the filiform papilli of the tongue. |
| 翻译后修饰 | Potential substrate of transglutaminase. Some arginines are probably converted. Phosphorylated upon DNA damage, probably by ATM or ATR. |
| 相似性 | Belongs to the S100-fused protein family. Contains 2 EF-hand domains. |
| 功能 | Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Repetin is a 784 amino acid secreted protein that belongs to the S100-fused protein family. Repetin is an extracellular epidermal matrix protein that is expressed in the epidermis and at high levels in eccrine sweat glands, the inner sheaths of hair roots and the filiform papilli of the tongue. A multifunctional epidermal matrix protein, repetin is involved in the cornified cell envelope formation. Containing two EF-hand domains, repetin’s recombinant N-terminal domain binds calcium reversibly. Repetin and trichohyalin may compensate for absent loricrin. The repetin gene contains three exons, two introns and spans at least 5.6 kb. The repetin gene is conserved in cow, mouse and rat, and maps to human chromosome 1q21.3. |
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Repetin Antibody Blocking Peptide(bs-9181P)-500ug
￥880
