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500ug
| 产品编号 | bs-7799P |
| 英文名称 | GAJ/MND1 Antibody Blocking Peptide |
| 中文名称 | 减数分裂核分裂蛋白1/GAJ封闭多肽 |
| 英文别名 | GAJ protein; Homolog of yeast MND1; Meiotic nuclear division 1, S. cerevisiae. homolog of antibody; Meiotic nuclear division protein 1 homolog; Meiotic nuclear divisions 1 homolog (S. cerevisiae); Meiotic nuclear divisions 1 homolog; MGC134110; MND1; RGD1309007; 2610034E18Rik; AI591601. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Cell Division > Other cell division antibodies |
| 亚基 | Heterodimer with PSMC3IP/HOP2. MND1-PSMC3IP interacts with DMC1 and RAD51 and binds preferentially to dsDNA. |
| 亚细胞定位 | Nucleus (Probable) |
| 相似性 | Belongs to the MND1 family. |
| 功能 | Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis (By similarity). Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The product of the GAJ gene associates with HOP2 to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 and DMC1. Both the MND1 and HOP2 genes are indispensable for meiotic recombination. |
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GAJ/MND1 Antibody Blocking Peptide(bs-7799P)-500ug
¥880







