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500ug
| 产品编号 | bs-9117P |
| 英文名称 | NRXN3 Antibody Blocking Peptide |
| 中文名称 | 轴突蛋白3 beta封闭多肽 |
| 英文别名 | Neurexin-3-beta; Neurexin III-beta; Neurexin-3-beta, soluble form; NRX3B_HUMAN; NRXN3; KIAA0743. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Cell Adhesion Proteins > Membrane Proteins Neuroscience > Cell Type Marker > Neuron marker > Synapse marker |
| 亚基 | The cytoplasmic C-terminal region binds to CASK. Binds to neuroligins NLGN1, NLGN2 and NLGN3. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein (Potential). |
| 组织特异性 | Expressed in the blood vessel walls (at protein level). |
| 翻译后修饰 | Proccessed by alpha-secretase leading to the formation of an extracellular soluble protein as well as a C-terminal membrane-embedded fragment (CTF). Proteolysis of these CTFs by gamma-secretase releases intracellular domains (ICDs) and extracellular peptides. |
| 相似性 | Belongs to the neurexin family.
Contains 1 laminin G-like domain. |
| 功能 | Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May play a role in angiogenesis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder. [provided by RefSeq, Dec 2012] |
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NRXN3 Antibody Blocking Peptide(bs-9117P)-500ug
¥880







