NRXN3 Antibody Blocking Peptide(bs-9117P)-500ug

NRXN3 Antibody Blocking Peptid

e(bs-9117P)-500ug
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  • bs-9117P
  • 2025年10月16日
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      500ug

    产品编号bs-9117P
    英文名称NRXN3 Antibody Blocking Peptide
    中文名称轴突蛋白3 beta封闭多肽
    英文别名Neurexin-3-beta; Neurexin III-beta; Neurexin-3-beta, soluble form; NRX3B_HUMAN; NRXN3; KIAA0743.
    纯化方法HPLC
    研究领域

    Neuroscience > Cell Adhesion Proteins > Membrane Proteins

    Neuroscience > Cell Type Marker > Neuron marker > Synapse marker

    亚基The cytoplasmic C-terminal region binds to CASK. Binds to neuroligins NLGN1, NLGN2 and NLGN3.
    亚细胞定位Membrane; Single-pass type I membrane protein (Potential).
    组织特异性Expressed in the blood vessel walls (at protein level).
    翻译后修饰Proccessed by alpha-secretase leading to the formation of an extracellular soluble protein as well as a C-terminal membrane-embedded fragment (CTF). Proteolysis of these CTFs by gamma-secretase releases intracellular domains (ICDs) and extracellular peptides.
    相似性Belongs to the neurexin family.
    Contains 1 laminin G-like domain.
    功能Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May play a role in angiogenesis.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder. [provided by RefSeq, Dec 2012]

     

     

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