- ￥880
- Bioss
- bs-20404P
- 2025年10月16日
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500ug
| 产品编号 | bs-20404P |
| 英文名称 | ALX1 Antibody Blocking Peptide |
| 中文名称 | 软骨蛋白1封闭多肽 |
| 英文别名 | ALX homeobox 1; ALX homeobox protein 1; ALX1; ALX1_HUMAN; CART 1; CART-1; CART1; Cartilage homeoprotein 1. |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Embryogenesis > Morphogens Developmental Biology > Organogenesis > Skeletal development > Bone Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families Stem Cells > Mesenchymal Stem Cells > Chondrogenesis |
| 亚基 | Interacts (via homeobox domain) with EP300. |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Cartilage and cervix tissue. |
| 翻译后修饰 | Acetylated at Lys-131 by EP300, leading to increased interaction with EP300 and enhances transcriptional activation activity. |
| 相似性 | Belongs to the paired homeobox family.
Contains 1 homeobox DNA-binding domain. |
| 功能 | Transcriptional activator that acts at a palindromic recognition sequence to enhance the activity of the SV40 and TK promoters. Functions as a repressor with the prolactin promoter in vivo. May play a role in chondrocyte differentiation and may also influence cervix development. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The specific function of this gene has yet to be determined in humans; however, in rodents, it is necessary for survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations in the mouse gene lead to neural tube defects such as acrania and meroanencephaly. [provided by RefSeq, Jul 2008]. |
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ALX1 Antibody Blocking Peptide(bs-20404P)-500ug
￥880
