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500ug
| 产品编号 | bs-1582P |
| 英文名称 | MBL2 Antibody Blocking Peptide |
| 中文名称 | 甘露聚糖结合凝集素封闭多肽 |
| 英文别名 | Mbl2; L-MBP; MBL; MBL-C; MBP-C; COLEC 1; COLEC1; HSMBPC; Mannan binding protein; Mannose binding lectin (protein C) 2 soluble; Mannose binding lectin 2 soluble; Mannose binding lectin; Mannose binding lectin protein C2 soluble opsonic defect; Mannose binding protein; Mannose binding protein C; Mannose binding protein C precursor; MBL 2; MBP 1; MBP; MBP C; MBP1; MBPC; MGC116832; MGC116833; Opsonic defect; protein C ; Soluble mannose binding lectin; MBL2_HUMAN. |
| 纯化方法 | HPLC |
| 亚基 | Oligomeric complex of 3 or more homotrimers. Interacts with MASP1 and MASP2. Interacts with MEP1A and MEP1B and may inhibit their catalytic activity. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Plasma protein produced mainly in the liver. |
| 相似性 | Contains 1 C-type lectin domain.
Contains 1 collagen-like domain. |
| 功能 | Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008]. |
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MBL2 Antibody Blocking Peptide(bs-1582P)-500ug
¥880







