- ￥880
- Bioss
- bs-9049P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-9049P |
| 英文名称 | TRPM1 Antibody Blocking Peptide |
| 中文名称 | 瞬时受体电位阳离子通道亚家族M成员1封闭多肽 |
| 英文别名 | Long transient receptor potential channel 1; LTRPC1; Melastatin 1; Melastatin-1; MLSN1; Transient receptor potential cation channel subfamily M member 1; Transient receptor potential cation channel, subfamily M, member 1; TRPM1; TRPM1 protein; TRPM1_HUMAN; Weakly similar to F54D1.5 [C.elegans]. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Metabolism > Plasma Membrane > Channels Signal Transduction > Signaling Pathway > Calcium Signaling > Calcium Channels |
| 亚细胞定位 | Cell membrane |
| 组织特异性 | Expressed in the retina where it localizes to the outer plexiform layer. Highly expressed in benign melanocytic nevi and diffusely expressed in various in situ melanomas, but not detected in melanoma metastases. Also expressed in melanocytes and pigmented metastatic melanoma cell lines. In melanocytes expression appears to be regulated at the level of transcription and mRNA processing. |
| 相似性 | Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM1 sub-subfamily. |
| 功能 | Cation channel essential for the depolarizing photoresponse of retinal ON bipolar cells. It is part of the GRM6 signaling cascade. May play a role in metastasis suppression (By similarity). May act as a spontaneously active, calcium-permeable plasma membrane channel. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Cation channel essential for the depolarizing photoresponse of retinal ON bipolar cells. It is part of the GRM6 signaling cascade. May play a role in metastasis suppression (By similarity). May act as a spontaneously active, calcium-permeable plasma membrane channel.Involvement in disease:Defects in TRPM1 are the cause of congenital stationary night blindness type 1C (CSNB1C) [MIM:613216]. A non-progressive retinal disorder characterized by impaired night vision, often associated with nystagmus and myopia. |
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TRPM1 Antibody Blocking Peptide(bs-9049P)-500ug
￥880
