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- Bioss
- bs-7682P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-7682P |
| 英文名称 | RBM38 Antibody Blocking Peptide |
| 中文名称 | RNA结合蛋白38封闭多肽 |
| 英文别名 | SEB4D; CLL associated antigen KW 5; CLL-associated antigen KW-5; HSRNASEB; RBM38; RBM38_HUMAN; RNA binding motif protein 38; RNA binding protein 38; RNA binding region (RNP1, RRM) containing 1; RNA binding region containing protein 1; RNA-binding motif protein 38; RNA-binding protein 38; RNA-binding region-containing protein 1; RNPC1; SEB4; SEB4B; ssDNA binding protein SEB4; ssDNA-binding protein SEB4. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Cell Cycle Inhibitors > Cip / Kip Developmental Biology > Organogenesis > Skeletal development > Muscle Epigenetics and Nuclear Signaling > Cell cycle > Cell Cycle Inhibitors > Cip/Kip Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing > Splicing Stem Cells > Mesenchymal Stem Cells > Myogenesis |
| 亚细胞定位 | Cytoplasm, cytosol. Nucleus. |
| 组织特异性 | Expressed in cardiac and skeletal muscle tissues. |
| 相似性 | Belongs to the RBM38 family. Contains 1 RRM (RNA recognition motif) domain. |
| 功能 | RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2 (By similarity). Plays a role in myogenic differentiation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation. |
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RBM38 Antibody Blocking Peptide(bs-7682P)-500ug
￥880
