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- Bioss
- bs-2947P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-2947P |
| 英文名称 | ERG25 Antibody Blocking Peptide |
| 中文名称 | 甲基固醇羟化酶单加氧酶1封闭多肽 |
| 英文别名 | 1500001G16Rik; C 4 methyl sterol; C78600; DESP4; ERG25; Methylsterol monooxygenase 1; MGC104344; MSMO1; MSMO1_HUMAN; OTTHUMP00000219757; OTTHUMP00000219758; OTTHUMP00000219759; OTTHUMP00000219760; sterol C4 methyl oxidase like. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of lipids and lipoproteins Cardiovascular > Lipids / Lipoproteins > Lipid Metabolism > Cholesterol Metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Cholesterol Metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism Signal Transduction > Metabolism > Lipid metabolism |
| 亚细胞定位 | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
| 相似性 | Belongs to the sterol desaturase family. |
| 功能 | Catalyzes the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Belonging to the sterol desaturase family, ERG25 is a 293 amino acid enzyme that performs the first of three enzymatic steps required to remove the two methyl groups leading to cholesterol. ERG25 is a multi-pass membrane protein that resides within the plasma membrane and the membrane of the endoplasmic reticulum. Concentrations of ERG25 mRNA increase when subjected to low iron growth conditions, suggesting that the enzyme is not regulated by iron but by an end product of the ergosterol pathway. Low-density lipoprotein (LDL) downregulates ERG25 expression in the vascular wall, an event that may be inhibited via SREBP overexpression. ERG25 is encoded by a gene located on human chromosome 4q32.3. |
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ERG25 Antibody Blocking Peptide(bs-2947P)-500ug
￥880
