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- bs-7658P
- 2025年10月16日
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500ug
| 产品编号 | bs-7658P |
| 英文名称 | CTNNBL1 Antibody Blocking Peptide |
| 中文名称 | β连环蛋白样蛋白1封闭多肽 |
| 英文别名 | Beta catenin like 1; Beta catenin like protein 1; Beta-catenin-like protein 1; C20orf33; Catenin beta like 1; Chromosome 20 open reading frame 3; CTBL1_HUMAN; CTNNBL 1; Ctnnbl1; NAP; Nuclear associated protein; nuclear protein NAP; Nuclear-associated protein; NYD SP19; P14 antibody P14L; Testis development protein NYD SP19; Testis development protein NYD-SP19. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cell Death > Apoptosis > Nucleus Cell Biology > Apoptosis > Nucleus Cell Biology > Other Antibodies > Other Antibodies |
| 亚基 | Component of the PRP19-CDC5L splicing complex composed of a core complex comprising a homotetramer of PRPF19, CDC5L, PLRG1 and BCAS2, and at least three less stably associated proteins CTNNBL1, CWC15 and HSPA8. Interacts directly with CWC15 and CDC5L in the complex. Interacts with AICDA; the interaction is important for the antibody diversification activity of AICDA. Interacts with PRPF31 (via its NLS). Interacts (via its N-terminal NLS) with KPNA1 and KPNA2. |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Widely expressed with highest levels in skeletal muscle, placenta, heart, spleen, testis and thyroid. |
| 功能 | Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs. In addition, the encoded protein contains Armadillo/beta-catenin-like repeats, which have been implicated in protein-protein interactions. Although the function of this protein has not been determined, the C-terminal portion of the protein has been shown to possess apoptosis-inducing activity. |
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CTNNBL1 Antibody Blocking Peptide(bs-7658P)-500ug
￥880
