FCRL6 Antibody Blocking Peptide(bs-16068P)-500ug

FCRL6 Antibody Blocking Peptid

e(bs-16068P)-500ug
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  • ¥880
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  • bs-16068P
  • 2025年10月16日
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      500ug

    产品编号bs-16068P
    英文名称FCRL6 Antibody Blocking Peptide
    中文名称FCRL6蛋白封闭多肽
    英文别名Fc receptor homolog 6; Fc receptor-like 6; Fc receptor-like protein 6; Fc receptor-like protein 7; FcR-like protein 6; FcRH6; FcRL6; Fcrl6; FCRL6_HUMAN; FLJ16056; IFGP6; IgSF type I transmembrane receptor; leukocyte receptor.
    纯化方法HPLC
    亚基Interacts with PTPN11.
    亚细胞定位Membrane.
    组织特异性Expressed by cytolytic cells including NK cells, effector and effector-memory CD8+ T-cells. Expression among T-cells is greatly expanded in HIV-1 infected individuals, and includes not only effector and effector-memory CD8+ T-cells but also populations of CD4+ T-cells.
    翻译后修饰Phosphorylated on Tyr residue, inducing association with PTPN11.
    相似性Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The Fc receptor homolog (FcRH) family of proteins are related to the classical Fc receptors (FcR) and belong to the immunoglobulin receptor superfamily. The proteins in the FcRH family are type I transmembrane glycoproteins and consist of FcRH1-FcRH6. The genes encoding the human FcRH proteins map to chromosome 1, near the related FCR genes. The FcRH proteins, which are involved in immune system regulation, have immunoreceptor-tyrosine inhibitory motifs in their cytoplasmic domains. Mutations in the gene encoding for the FcRH proteins may be associated with systemic lupus erythematosus, autoimmune thyroid disease and rheumatoid arthritis. The FcRH genes are expressed primarily, although not exclusively, by mature B lineage cells, and may serve important regulatory roles in normal and neoplastic B cell development.

     

     

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