- ￥880
- Bioss
- bs-20234P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-20234P |
| 英文名称 | GRK1 Antibody Blocking Peptide |
| 中文名称 | G蛋白偶合受体激酶1封闭多肽 |
| 英文别名 | G-protein coupled receptor kinase 1; GRK1; GPRK1; RK; Grk1; Rhok; RHODOPSIN KINASE; RK_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurotransmission > Intracellular Signaling > Kinases Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR Neuroscience > Sensory System > Visual system Signal Transduction > Protein Phosphorylation > Tyrosine Kinases > Receptor Tyrosine Kinases |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Retina and pineal gland. |
| 翻译后修饰 | Autophosphorylated. Farnesylation is required for full activity. |
| 相似性 | Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
GPRK subfamily. Contains 1 AGC-kinase C-terminal domain. Contains 1 protein kinase domain. Contains 1 RGS domain. |
| 功能 | Phosphorylates rhodopsin thereby initiating its deactivation. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). [provided by RefSeq] |
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GRK1 Antibody Blocking Peptide(bs-20234P)-500ug
￥880
