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- bs-21231P
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500ug
| 产品编号 | bs-21231P |
| 英文名称 | SLC25A33 Antibody Blocking Peptide |
| 中文名称 | 溶质载体家族25成员33封闭多肽 |
| 英文别名 | BMSC MCP; BMSC-MCP; Bone marrow stromal cell mitochondrial carrier protein; HuBMSC MCP; HuBMSC-MCP; MGC4399; Mitochondrial carrier protein; Novel mitochondrial carrier protein; PNC1 protein; Protein PNC1; S2533_HUMAN; Slc25a33; Solute carrier family 25 member 33. |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers Metabolism > Types of disease > Cancer Signal Transduction > Metabolism > Mitochondrial |
| 亚细胞定位 | Mitochondrion inner membrane. |
| 组织特异性 | Expressed in the central nervous system. Also expressed in testis and skeletal muscle. Weakly expressed in heart, liver, kidney, prostate, colon and peripheral blood leukocytes. |
| 相似性 | Belongs to the mitochondrial carrier family. Contains 3 Solcar repeats. |
| 功能 | Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria (PubMed:25320081). Transports preferentially uracil, thymine, and cytosine (deoxy)nucleoside di- and triphosphates by an antiport mechanism (PubMed:25320081). Also transports guanine but not adenine (deoxy)nucleotides (PubMed:25320081). Is inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials (mercury dichloride, mersalyl acid, p-hydroxymercuribenzoate) (PubMed:25320081). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration (PubMed:20453889). Upon INS or IGF1 stimulation regulates cell growth and proliferation by controlling mitochondrial DNA replication and transcription, the ratio of mitochondria-to nuclear-encoded components of the electron transport chain resulting in control of mitochondrial ROS production (PubMed:20453889, PubMed:17596519). Participates in dendritic cell endocytosis and may associate with mitochondrial oxidative phosphorylation (PubMed:14715278). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | SLC25A33 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008] |
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SLC25A33 Antibody Blocking Peptide(bs-21231P)-500ug
￥880
