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- bs-8873P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-8873P |
| 英文名称 | CD36 Antibody Blocking Peptide |
| 中文名称 | CD36封闭多肽 |
| 英文别名 | Platelet glycoprotein IV; GPIV; lycoprotein IIIb; GPIIIB; Leukocyte differentiation antigen CD36; PAS IV; Platelet collagen receptor; Fatty acid translocase; FAT; Thrombospondin receptor; CD36_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of lipids and lipoproteins Cardiovascular > Angiogenesis > Endothelial Cell Markers Cardiovascular > Atherosclerosis > Lipid transport Cardiovascular > Blood > Platelets Immunology > Cell Type Markers > CD > Platelets Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism Metabolism > Types of disease > Heart disease Microbiology > Protein > Human Protein > Defensin Stem Cells > Endothelial Progenitors > Endothelial Markers Stem Cells > Hematopoietic Progenitors > Hematopoietic Stem Cells > Human Lineage Negative |
| 亚基 | Interacts with THBS1 and THBS2; the interactions mediate the THBS antiangiogenic activity. |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. |
| 组织特异性 | Predominant in heart, intestine, spleen, fat, skeletal muscle, lower in testes. |
| 翻译后修饰 | N-glycosylated and O-glycosylated with a ratio of 2:1. |
| 相似性 | Belongs to the CD36 family. |
| 功能 | Seems to have numerous potential physiological functions. Binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014] |
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